Trizol

TRIzol reagent contains guanidinium thiocyanate and phenol.

TRIzol is a widely used[1] chemical solution used in the extraction of DNA, RNA, and proteins from cells. The solution was initially used and published by Piotr Chomczyński and Nicoletta Sacchi in 1987.[2]

TRIzol is the brand name of guanidinium thiocyanate from the Ambion part of Life Technologies,[3] and Tri-Reagent is the brand name from MRC,[4] which was founded by Chomczynski.

  1. ^ "Total RNA isolation: Trizol vs RNeasy". www.bioastrum.com. Retrieved 2021-08-18.
  2. ^ Chomczynski, P; Sacchi, N (April 1987). "Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction". Anal. Biochem. 162 (1): 156–9. doi:10.1016/0003-2697(87)90021-2. PMID 2440339.
  3. ^ Life Technologies
  4. ^ Molecular Research Center, Inc.