Trypanosomiasis

Trypanosomiasis
SpecialtyInfectious diseases, veterinary medicine Edit this on Wikidata

Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. In humans this includes African trypanosomiasis and Chagas disease. A number of other diseases occur in other animals.

African trypanosomiasis, which is caused by either Trypanosoma brucei gambiense or Trypanosoma brucei rhodesiense, threatens some 65 million people in sub-Saharan Africa, especially in rural areas and populations disrupted by war or poverty. The number of cases has been going down due to systematic eradication efforts: in 1998 almost 40,000 cases were reported but almost 300,000 cases were suspected to have occurred; in 2009, the number dropped below 10,000; and in 2018 it dropped below 1000.[1] Chagas disease causes 21,000 deaths per year mainly in Latin America.[2]

  1. ^ WHO. "Trypanosomiasis, Human African (sleeping sickness)". Fact sheet N°259. World Health Organization. Retrieved 25 February 2014.
  2. ^ Maya JD, Cassels BK, Iturriaga-Vásquez P, et al. (2007). "Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host". Comp. Biochem. Physiol. A. 146 (4): 601–20. doi:10.1016/j.cbpa.2006.03.004. PMID 16626984.