| Tryphaena | |
|---|---|
| Queen consort of the Seleucid Empire | |
| Tenure | 124 BC–111 BC (in opposition to her sister Cleopatra IV until 112 BC) |
| Coronation | 124 BC |
| Predecessors | Cleopatra Thea and Seleucus V Philometor |
| Successor | Queen consort Cleopatra Selene |
| Born | c. 141 BC |
| Died | 111 BC |
| Spouse | Antiochus VIII Grypus |
| Issue | |
| Dynasty | Ptolemaic |
| Father | Ptolemy VIII Physcon |
| Mother | Cleopatra III |
Tryphaena (Greek: Τρύφαινα; c. 141 BC – 111 BC) was a Ptolemaic princess. She married the Seleucid king Antiochus VIII Grypus and was queen of Syria (124–111 BC).