Tupac Shakur (1971–1996) was an American rapper, songwriter, and actor.
Tupac may also refer to:
- Tupac (name), a list of people with the given name
- Operation Tupac, Inter-Services Intelligence activities in India
- "Tupac", a song by DaBaby from his 2019 album Baby on Baby
- "2 Pac", a song by Future from his 2014 mixtape Monster