| Tupuxuara Temporal range: Albian,
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| Reconstructed skeleton of T. leonardii, American Museum of Natural History | |
Scientific classification 
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| Domain: | Eukaryota |
| Kingdom: | Animalia |
| Phylum: | Chordata |
| Order: | †Pterosauria |
| Suborder: | †Pterodactyloidea |
| Subfamily: | †Thalassodrominae |
| Genus: | †Tupuxuara Kellner & Campos, 1988 |
| Type species | |
| †Tupuxuara longicristatus Kellner & Campos, 1988
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| Other species | |
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Tupuxuara is a genus of large, crested, and toothless pterodactyloid pterosaur from the Early Cretaceous period (Albian stage) of what is now the Romualdo Formation of the Santana Group, Brazil, about 125 to 112 million years ago. Tupuxuara is a close relative of Thalassodromeus, and both form a group that is either called Thalassodrominae (if placed within the family Tapejaridae) or Thalassodromidae (if placed within the clade Neoazhdarchia).