"Twenty Vicodin" is the eighth season premiere episode of the American television medical drama series House and the 156th overall episode of the series.[4] It aired on Fox on October 3, 2011. The episode introduces a new regular cast member to the series, Odette Annable, who plays Dr. Jessica Adams.[5]Jaleel White, who played Steve Urkel on the ABC show Family Matters, makes a guest appearance in the episode.[6] In the episode, the storyline picks up eleven months after the season seventh finale with House in prison.[7]