The type III secretion system (T3SS or TTSS) is one of the bacterial secretion systems used by bacteria to secrete their effector proteins into the host's cells to promote virulence and colonisation.[1][2] While the type III secretion system has been widely regarded as equivalent to the injectisome, many argue that the injectisome is only part of the type III secretion system, which also include structures like the flagellar export apparatus.[3] The T3SS is a needle-like protein complex found in several species of pathogenic gram-negative bacteria.
- ^ Lara-Tejero M, Galán JE (March 2019). "The Injectisome, a Complex Nanomachine for Protein Injection into Mammalian Cells". EcoSal Plus. 8 (2). doi:10.1128/ecosalplus.ESP-0039-2018. PMC 6450406. PMID 30942149.
- ^ McHugh RE, O'Boyle N, Connolly JP, Hoskisson PA, Roe AJ (February 2019). "Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis". Infection and Immunity. 87 (2): e00595–18. doi:10.1128/IAI.00595-18. PMC 6346137. PMID 30455200.
- ^ Halte M, Erhardt M (January 2021). "Protein Export via the Type III Secretion System of the Bacterial Flagellum". Biomolecules. 11 (2): 186. doi:10.3390/biom11020186. PMC 7911332. PMID 33572887.