U.S. Route 401

U.S. Route 401 marker
U.S. Route 401
Map
US 401 highlighted in red
Route information
Auxiliary route of US 1
Length251.0 mi[citation needed] (403.9 km)
Existed1957–present
Major junctions
South end
US 76 Bus. / US 521 in Sumter, SC
Major intersections
North end I-85 / US 1 near Wise, NC
Location
CountryUnited States
StatesSouth Carolina, North Carolina
CountiesSC: Sumter, Lee, Darlington, Marlboro
NC: Scotland, Hoke, Cumberland, Harnett, Wake, Franklin, Warren
Highway system

SC 400SC SC 402
NC 400NC NC 403

U.S. Route 401 (US 401) is a north–south United States highway, a spur of U.S. Route 1, that travels along the Fall Line from Sumter, South Carolina to Interstate 85 near Wise, North Carolina.