Section of U.S. Highway in Kentucky
This article is about the section of U.S. Route 421 in Kentucky. For the entire route, see
U.S. Route 421.
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US 421 highlighted in red |
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Maintained by KYTC |
Length | 250.536 mi[1] (403.199 km) |
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South end | US 421 at the Virginia state line near Pennington Gap, VA |
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Major intersections | |
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North end | US 421 at the Indiana state line near Madison |
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Country | United States |
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State | Kentucky |
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Counties | Harlan, Leslie, Clay, Jackson, Rockcastle, Madison, Fayette, Scott, Woodford, Franklin, Shelby, Henry, Trimble |
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- Kentucky State Highway System
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U.S. Route 421 (US 421) in the U.S. state of Kentucky is a 250.536-mile-long (403.199 km) north–south United States highway that traverses twelve counties in the central and eastern parts of the state. It travels in a southeast-to-northwest path from the Virginia state line near Pennington Gap to the Indiana state line, on the Ohio River at Milton, Kentucky and Madison, Indiana.[2]