U.S. Route 64 in Oklahoma

U.S. Highway 64
US 64 highlighted in red
Route information
Maintained by ODOT
Length	591.17 mi[1] (951.40 km)
Existed	November 11, 1926[2]–present
Major junctions
West end	US 56 / US 64 / US 412 at the New Mexico state line
Major intersections	I-35 near Enid I-44 in Tulsa I-40 in Sallisaw and Roland
East end	US 64 at the Arkansas state line
Location
Country	United States
State	Oklahoma
Counties	Cimarron, Texas, Beaver, Harper, Woods, Alfalfa, Grant, Garfield, Noble, Pawnee, Osage, Tulsa, Wagoner, Muskogee, Sequoyah
Highway system
United States Numbered Highway System List Special Divided Oklahoma State Highway System Interstate US State Turnpikes
← SH-63 → SH-65

U.S. Route 64 (US-64) is a U.S. highway running from the Four Corners area to the Outer Banks of North Carolina. Between these two points, the highway passes through the entire width of Oklahoma; a total of 591.17 miles (951.40 km) of US-64 lies in the state of Oklahoma. US-64 enters the state from New Mexico, crossing the line between the two states between Clayton, New Mexico, and Boise City in Cimarron County. The route runs the full length of the Oklahoma Panhandle, then serves the northernmost tier of counties in the main body of the state before dipping southeastward to Tulsa, the state's second-largest city. From Tulsa, the highway continues southeast, leaving Oklahoma just west of Fort Smith, Arkansas. In addition to Tulsa, US-64 serves fifteen Oklahoma counties and the cities of Guymon, Woodward, Enid, and Muskogee.

US-64 has been a part of the United States Numbered Highways system from the program's inception in 1926. US-64's route has remained roughly the same since then, although it has undergone alterations several times, mainly changing its course through towns and moving the highway designation to higher-capacity expressways and freeways.