U11 spliceosomal RNA

U11 spliceosomal RNA
Secondary structure of human U11 spliceosomal RNA
Identifiers
SymbolU11
RfamRF00548
Other data
RNA typeGene; snRNA; splicing
Domain(s)Eukaryota
GOGO:0000369 GO:0030627 GO:0005692
SOSO:0000398
PDB structuresPDBe

The U11 snRNA (small nuclear ribonucleic acid) is an important non-coding RNA in the minor spliceosome protein complex, which activates the alternative splicing mechanism. The minor spliceosome is associated with similar protein components as the major spliceosome. It uses U11 snRNA to recognize the 5' splice site (functionally equivalent to U1 snRNA) while U12 snRNA binds to the branchpoint to recognize the 3' splice site (functionally equivalent to U2 snRNA).[1]

  1. ^ Elliot, David; Ladomery, Michael (2011). Molecular Biology of RNA. Oxford University Press. p. 124.