The UAAP Season 78 seniors division football tournament started on February 7, 2016, following the shift in the start of the league. The tournament opened at Emperador McKinley Hill Stadium in Fort Bonifacio, Taguig City. Other games were held at the Moro Lorenzo Football Field of Ateneo de Manila University in Katipunan Ave., Loyola Heights, Quezon City. Ateneo was the tournament host.
The men's and women's Final matches happened on May 5, 2016, which is exactly eight months after the start of the Season last September 5, 2015. The championship games also served as the last ones for the Season, making football the final event.