The Usmani family of Deoband are the descendants of the third caliph Uthman (r. 644–656) based primarily in the town of Deoband in India. The notable people of this family include Fazlur Rahman Usmani, Mahmud Hasan Deobandi, Azizur Rahman Usmani and Shabbir Ahmad Usmani.
Fazlur Rahman Usmani, Nehal Ahmad, Mehtab Ali and Zulfiqar Ali Deobandi from the family were co-founders of Darul Uloom Deoband. Atiqur Rahman Usmani, a member of this family, co-founded Nadwatul Musannifeen and All India Muslim Majlis-e-Mushawarat.