VBS may refer to:
- Brescia Airport's IATA airport code;
- Vacation Bible School;
- Valley Beth Shalom, a synagogue in Encino, California, US;
- Value breakdown structure in project management;
- .vbs, the file extension for VBScript scripts;
- VBScript, a programming language developed by Microsoft;
- VBS.tv, the broadband video network of Vice magazine;
- Vereinigte Breslauer Sportfreunde, a defunct German football club;
- Vetting and Barring Scheme of the Independent Safeguarding Authority, UK;
- Vividh Bharati Service, an Indian radio channel;
- VBS Mutual Bank, a defunct South African mutual bank;
- Video Baseband Signal, an unmodulated analog B/W video signal used e.g., by the Composite Video standard;
- Virtualization Based Security, a feature of the Microsoft Windows operating system;
- VBS, a military tactical shooter simulation used for dismounted infantry training by the USMC, the US Army, and a number of the NATO armed forces.