VLA-4

Integrin beta-1
Integrin beta-1
Identifiers
Symbol	ITGB1
Alt. symbols	CD29
Alt. names	Fibronectin receptor subunit beta
NCBI gene	3688
HGNC	6153
OMIM	135630
RefSeq	NP_002202
UniProt	P05556
Other data
Locus	Chr. 10 p11.22
Structures
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Structures	Swiss-model
Domains	InterPro

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Structures	Swiss-model
Domains	InterPro

Integrin alpha-4
Integrin alpha-4
Identifiers
Symbol	ITGA4
Alt. names	CD49 antigen-like family member D
NCBI gene	3676
HGNC	6140
OMIM	192975
RefSeq	NP_000876
UniProt	P13612
Other data
Locus	Chr. 2 q31.3
Structures
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Structures	Swiss-model
Domains	InterPro

Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the beta 1 subunit is 150 kDa.^[1]

^ Yang GX, Hagmann WK (May 2003). "VLA-4 antagonists: potent inhibitors of lymphocyte migration". Medicinal Research Reviews. 23 (3): 369–92. doi:10.1002/med.10044. PMID 12647315. S2CID 42804611.

[Yang_2003-1] Yang GX, Hagmann WK (May 2003). "VLA-4 antagonists: potent inhibitors of lymphocyte migration". Medicinal Research Reviews. 23 (3): 369–92. doi:10.1002/med.10044. PMID 12647315. S2CID 42804611.

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