VPS29

VPS29
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1W24, 2R17
Identifiers
Aliases	VPS29, DC15, PEP11, DC7, VPS29 retromer complex component, retromer complex component
External IDs	OMIM: 606932; MGI: 1928344; HomoloGene: 9433; GeneCards: VPS29; OMA:VPS29 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	110,502,111 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	122,503,047 bp
RNA expression pattern
	Top expressed in
	monocyte; ; tibialis anterior muscle; ; mucosa of ileum; ; smooth muscle tissue; ; myocardium of left ventricle; ; gastric mucosa; ; rectum; ; cardiac muscle tissue of right atrium; ; right coronary artery; ; tibial arteries;
	Top expressed in
	otic placode; ; facial motor nucleus; ; saccule; ; barrel cortex; ; yolk sac; ; endocardial cushion; ; endothelial cell of lymphatic vessel; ; atrioventricular valve; ; anterior horn of spinal cord; ; nucleus accumbens;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; metal ion binding; zinc ion binding;
Cellular component	late endosome; early endosome; endosome membrane; membrane; intracellular membrane-bounded organelle; cytoplasm; cytosol; retromer complex; retromer, cargo-selective complex; endosome;
Biological process	protein transport; Wnt signaling pathway; regulation of autophagy; intracellular protein transport; retrograde transport, endosome to Golgi; viral process; endocytic recycling;
	Sources:Amigo / QuickGO
Orthologs
	51699
	56433
	ENSG00000111237
	ENSMUSG00000029462
	Q9UBQ0; Q05DG7
	Q9QZ88
	NM_001282150; NM_001282151; NM_016226; NM_057180
	NM_019780; NM_001347453; NM_001359226
	NP_001269079; NP_001269080; NP_057310; NP_476528
	NP_001334382; NP_062754; NP_001346155
	Wikidata
View/Edit Human	View/Edit Mouse

VPS29 is a human gene coding for the vacuolar protein sorting protein Vps29, a component of the retromer complex.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111237 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029462 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Edgar AJ, Polak JM (November 2000). "Human homologues of yeast vacuolar protein sorting 29 and 35". Biochem. Biophys. Res. Commun. 277 (3): 622–30. doi:10.1006/bbrc.2000.3727. PMID 11062004.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111237 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029462 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11062004-5] Edgar AJ, Polak JM (November 2000). "Human homologues of yeast vacuolar protein sorting 29 and 35". Biochem. Biophys. Res. Commun. 277 (3): 622–30. doi:10.1006/bbrc.2000.3727. PMID 11062004.

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