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| Combination of | |
|---|---|
| Valsartan | Angiotensin II receptor antagonist |
| Hydrochlorothiazide | Thiazide diuretic |
| Clinical data | |
| Trade names | Co-vasotec, Diovan HCT, Co-Diovan, others |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a611032 |
| License data | |
| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| PubChem CID | |
| KEGG | |
| CompTox Dashboard (EPA) | |
| (verify) | |
Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient.[6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic.[7] It is taken by mouth.[7]
Common side effects include dizziness and headaches.[7] Serious side effects may include allergic reactions, electrolyte abnormalities, and glaucoma.[2] Use in pregnancy is not recommended.[2]
The combination was approved for medical use in the United States in 1998.[7] It is available as a generic medication.[6] In 2021, it was the 224th most commonly prescribed medication in the United States, with more than 1 million prescriptions.[8][9]
- ^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
- ^ a b c "Diovan HCT- valsartan and hydrochlorothiazide tablet, film coated". DailyMed. Retrieved 20 January 2021.
- ^ "Active substance: valsartan, hydrochlorothiazide / valsartan" (PDF). List of nationally authorised medicinal products. European Medicines Agency. 14 January 2021.
- ^ "Dafiro HCT EPAR". European Medicines Agency (EMA). Retrieved 21 April 2021.
- ^ "Exforge HCT EPAR". European Medicines Agency (EMA). Retrieved 21 April 2021.
- ^ a b British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 179. ISBN 9780857113382.
- ^ a b c d "Hydrochlorothiazide and valsartan Uses, Side Effects & Warnings". Drugs.com. Retrieved 10 March 2019.
- ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Hydrochlorothiazide; Valsartan - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.