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COVID-19 pandemic
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Scientifically accurate atomic model of the external structure of SARS-CoV-2. Each "ball" is an atom.
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Positive, negative, and neutral mutations during the evolution of coronaviruses like SARS-CoV-2.

Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are viruses that, while similar to the original, have genetic changes that are of enough significance to lead virologists to label them separately. SARS-CoV-2 is the virus that causes coronavirus disease 2019 (COVID-19). Some have been stated, to be of particular importance due to their potential for increased transmissibility,^[1] increased virulence, or reduced effectiveness of vaccines against them.^[2]^[3] These variants contribute to the continuation of the COVID-19 pandemic.

As of 24 September 2024^[update], the variants of interest as specified by the World Health Organization are BA.2.86 and JN.1, and the variants under monitoring are JN.1.7, KP.2, KP.3, KP.3.1.1, JN.1.18, LB.1, and XEC.^[4]

^ Shahhosseini N, Babuadze GG, Wong G, Kobinger GP (April 2021). "Mutation Signatures and In Silico Docking of Novel SARS-CoV-2 Variants of Concern". Microorganisms. 9 (5): 926. doi:10.3390/microorganisms9050926. PMC 8146828. PMID 33925854. S2CID 233460887.
^ "Coronavirus variants and mutations: The science explained". BBC News. 6 January 2021. Archived from the original on 22 February 2021. Retrieved 2 February 2021.
^ Kupferschmidt K (15 January 2021). "New coronavirus variants could cause more reinfections, require updated vaccines". Science. doi:10.1126/science.abg6028. S2CID 234141081. Archived from the original on 22 February 2021. Retrieved 2 February 2021.
^ "WHO Coronavirus Network (CoViNet)". Retrieved 1 September 2024.

Variants of SARS-CoV-2