Vern L. Schramm | |
|---|---|
 Schramm in 2004 | |
| Born | November 9, 1941 (age 82) Howard, South Dakota, U.S. |
| Alma mater | South Dakota State University |
| Known for | Enzyme kinetics, Kinetic isotope effect |
| Awards | Rudi Lemberg Award, Repligen Award |
| Scientific career | |
| Fields | Biochemistry |
| Institutions | Albert Einstein College of Medicine |
| Doctoral advisor | John F. Morrison |
Vern L. Schramm (born November 9, 1941) is a professor and Ruth Merns Chair in Biochemistry at the Albert Einstein College of Medicine of Yeshiva University.[1][2] Schramm was elected to the National Academy of Sciences in 2007.[3][4] His laboratory's research focuses on the elucidation of enzymatic mechanisms and transition state structure.[4]
This information is then used for the logical design of transition-state inhibitors which have the potential to be new biologically active agents. Some of these are in development to be drugs. Schramm's work has translated basic chemical understanding at the quantum mechanical level to a new approach to drug development.[5]
- ^ "Einstein Faculty: Vern L. Schramm, Ph.D." Retrieved 2010-01-18.
- ^ "Vern L Schramm - ComBio 2009, Christchurch, New Zealand". Retrieved 2010-01-18.
- ^ "Einstein's Dr. Vern Schramm elected to the National Academy of Sciences". Retrieved 2010-01-18.
- ^ a b "Einstein's Dr. Vern Schramm elected to the National Academy of Sciences". Bio-Medicine. May 1, 2007. Retrieved 2010-01-18.
- ^ Schramm VL (2011). "Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimes". Annual Review of Biochemistry. 80: 703–32. doi:10.1146/annurev-biochem-061809-100742. PMC 5502542. PMID 21675920.