Vesicle-associated membrane protein 7

VAMP7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DMW
Identifiers
Aliases	VAMP7, SYBL1, TI-VAMP, TIVAMP, VAMP-7, vesicle associated membrane protein 7
External IDs	OMIM: 300053; MGI: 1096399; HomoloGene: 4121; GeneCards: VAMP7; OMA:VAMP7 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	155,943,769 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; monocyte; ; endothelial cell; ; visceral pleura; ; parietal pleura; ; glomerulus; ; trabecular bone; ; kidney tubule; ; metanephric glomerulus; ; tibia;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SNARE binding; SNAP receptor activity; syntaxin binding; protein binding;
Cellular component	extracellular exosome; transport vesicle; pseudopodium; cytoplasm; transport vesicle membrane; synapse; integral component of membrane; trans-Golgi network; azurophil granule membrane; Golgi apparatus; cell junction; platelet alpha granule; intracellular membrane-bounded organelle; lamellipodium; apical part of cell; neuron projection; membrane; cell surface; phagocytic vesicle membrane; endoplasmic reticulum; perinuclear region of cytoplasm; endoplasmic reticulum membrane; secretory granule; secretory granule membrane; lysosome; cytoplasmic vesicle; late endosome membrane; endosome; phagocytic vesicle; plasma membrane; lysosomal membrane; SNARE complex; clathrin-coated vesicle membrane; synaptic vesicle; integral component of synaptic vesicle membrane; hippocampal mossy fiber to CA3 synapse;
Biological process	autophagosome maturation; vesicle transport along microtubule; vesicle fusion with Golgi apparatus; Golgi to plasma membrane protein transport; positive regulation of histamine secretion by mast cell; SNARE complex assembly; calcium-ion regulated exocytosis; triglyceride transport; endoplasmic reticulum to Golgi vesicle-mediated transport; post-Golgi vesicle-mediated transport; regulation of protein targeting to vacuolar membrane; exocytosis; natural killer cell degranulation; phagocytosis, engulfment; protein transport; endosome to lysosome transport; positive regulation of dendrite morphogenesis; vesicle fusion; vesicle-mediated transport; neutrophil degranulation; eosinophil degranulation; endocytosis; membrane organization; transport;
	Sources:Amigo / QuickGO
Orthologs
	6845
	20955
	ENSG00000124333
	ENSMUSG00000051412
	P51809
	P70280
	NM_001145149; NM_001185183; NM_005638
	NM_001302138; NM_011515; NM_001359151
	NP_001138621; NP_001172112; NP_005629
	NP_001289067; NP_035645; NP_001346080
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicle-associated membrane protein 7 (VAMP-7), is a protein that in humans is encoded by the VAMP7 gene also known as the SYBL1 gene.^[4]^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124333 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ D'Esposito M, Ciccodicola A, Gianfrancesco F, Esposito T, Flagiello L, Mazzarella R, Schlessinger D, D'Urso M (Jul 1996). "A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation". Nat. Genet. 13 (2): 227–9. doi:10.1038/ng0696-227. PMID 8640232. S2CID 8466678.
^ Filippini F, Rossi V, Galli T, Budillon A, D'Urso M, D'Esposito M (Jul 2001). "Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain". Trends Biochem. Sci. 26 (7): 407–9. doi:10.1016/S0968-0004(01)01861-8. PMID 11440841.
^ "Entrez Gene: SYBL1 synaptobrevin-like 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124333 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8640232-4] D'Esposito M, Ciccodicola A, Gianfrancesco F, Esposito T, Flagiello L, Mazzarella R, Schlessinger D, D'Urso M (Jul 1996). "A synaptobrevin-like gene in the Xq28 pseudoautosomal region undergoes X inactivation". Nat. Genet. 13 (2): 227–9. doi:10.1038/ng0696-227. PMID 8640232. S2CID 8466678.

[pmid11440841-5] Filippini F, Rossi V, Galli T, Budillon A, D'Urso M, D'Esposito M (Jul 2001). "Longins: a new evolutionary conserved VAMP family sharing a novel SNARE domain". Trends Biochem. Sci. 26 (7): 407–9. doi:10.1016/S0968-0004(01)01861-8. PMID 11440841.

[entrez-6] "Entrez Gene: SYBL1 synaptobrevin-like 1".

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