Vinconate

Vinconate
Clinical data
ATC code
  • none
Identifiers
  • methyl (3aS)-3-ethyl-2,3,3a,4-tetrahydro-1H-indolo[3,2,1-de]-1,5-maphthyridine-6-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.067.969 Edit this at Wikidata
Chemical and physical data
FormulaC18H20N2O2
Molar mass296.370 g·mol−1
3D model (JSmol)
  • O=C(OC)C/1=C/CC3c2n\1c4ccccc4c2CCN3CC
  • InChI=1S/C18H20N2O2/c1-3-19-11-10-13-12-6-4-5-7-14(12)20-16(18(21)22-2)9-8-15(19)17(13)20/h4-7,9,15H,3,8,10-11H2,1-2H3 checkY
  • Key:JWOSSISWAJNJIA-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Vinconate is a synthetic vincamine analog used as a nootropic.[1]

Vinconate, even when systemically administered, enhances the endogenous release of dopamine in the striatum, probably via the stimulation of presynaptic muscarinic receptors.[2]

  1. ^ Brimble MA, Levi MS (2010). "A Review of Neuroprotective Agents". In Atta-ur-Rahman, Reitz AB (eds.). Frontiers in Medicinal Chemistry. Vol. 3. SAIF Zone: Bentham Science Publishers. p. 182. ISBN 978-1-60805-206-6.
  2. ^ Iino T, Katsura M, Kuriyama K. Effect of vinconate on the extracellular levels of dopamine and its metabolites in the rat striatum: microdialysis studies. Eur J Pharmacol. 1995 Nov 3;286(1):99-103. doi: 10.1016/0014-2999(95)00545-v. PMID: 8566157.