William Henry Clark (c.1815–1870) was an early settler and brewer in Adelaide, in the Colony of South Australia. He was the founder of the Halifax Street Brewery around 1844 (sold in 1856), and in 1859 was responsible for the building of a brewery at the western end of Hindley Street. However he fell into insolvency, leaving the state in 1860 to avoid his debtors, and the Hindley Street brewery taken over by William Knox Simms, later becoming the West End Brewery.