The second season of Prison Break, an American serial drama television series, commenced airing in the United States on August 21, 2006, on Mondays at 9:00 pm (EST) on the Fox Broadcasting Company. Prison Break was produced by Adelstein-Parouse Productions, in association with Rat Entertainment, Original Film and 20th Century Fox Television. The season contains 22 episodes, and concluded on April 2, 2007. Prison Break revolves around two brothers: one who has been sentenced to death for a crime he did not commit, and his younger sibling, a genius who devises an elaborate plan to help him escape prison. The brothers, along with six other prisoners at Fox River State Penitentiary, manage to escape, and the second season follows a massive manhunt chasing the group. For the season, three characters are downgraded from series regular to recurring status, and a new character is introduced. Filming took place in Dallas, Texas, due to a close proximity of rural and urban settings. For the final three episodes, scenes were filmed in Pensacola, Florida, to represent Panama. (Full list...)