William Appleton | |
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| Member of the U.S. House of Representatives from Massachusetts | |
| In office March 4, 1851 – March 3, 1855 | |
| Preceded by | Samuel Atkins Eliot |
| Succeeded by | Anson Burlingame |
| Constituency | 1st district (1851–53) 5th district (1853–55) |
| In office March 4, 1861 – September 27, 1861 | |
| Preceded by | Anson Burlingame |
| Succeeded by | Samuel Hooper |
| Constituency | 5th district |
| Personal details | |
| Born | November 16, 1786 Brookfield, Massachusetts, U.S. |
| Died | February 15, 1862 (aged 75) Longwood, Massachusetts, U.S. |
| Political party | Whig Constitutional Union |
| Spouse | Mary Ann Cutler |
| Relatives | Appleton family |
| Profession | Politician, Banker, Merchant |
William Appleton (November 16, 1786 – February 15, 1862) was an American businessman and politician from Massachusetts. He was a trader, shipowner, and banker, and served as a U.S. representative from Massachusetts from 1851 to 1855, and again from 1861 to 1862.