Sir William Brabazon (died 1552), was an English-born soldier and statesman in Ireland. He held office as Vice-Treasurer of Ireland and Lord Justice of Ireland. His descendants still hold the title Earl of Meath.
Brabazon was descended from the family of Roger le Brabazon, and was the son of John Brabazon of Eastwell, Leicestershire; his mother was a Miss Chaworth. His grandfather, John Brabazon the elder, had been killed at the Battle of Bosworth.