Wilms' tumor

Wilms' tumor
Other namesWilms' tumor
Nephroblastoma
High magnification micrograph showing the three elements of Wilms' tumor. H&E stain.
Pronunciation
SpecialtyOncology, urology, nephrology
Usual onset1–4 years old[1]
TreatmentNephrectomy
Radiotherapy
Prognosis~90% of children are cured[2]
Frequency~500 new diagnoses per year (United States)[1]
Named afterMax Wilms

Wilms' tumor or Wilms tumor,[3] also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children (rarely in adults),[4] and occurs most commonly as a renal tumor in child patients.[5][6] It is named after Max Wilms, the German surgeon (1867–1918) who first described it.[7]

Approximately 650 cases are diagnosed in the U.S. annually.[2] The majority of cases occur in children with no associated genetic syndromes; however, a minority of children with Wilms' tumor have a congenital abnormality.[2]  It is highly responsive to treatment, with about 90 percent of children being cured.[2]

  1. ^ a b "Wilms' tumor". Mayo Clinic. Retrieved March 10, 2022.
  2. ^ a b c d "Wilms Tumor and Other Childhood Kidney Tumors Treatment". National Cancer Institute. Retrieved 2018-11-12.
  3. ^ "Wilms tumor: MedlinePlus Genetics". medlineplus.gov. Retrieved 11 June 2022.
  4. ^ EBSCO database verified by URAC; accessed from Mount Sinai Hospital, New York
  5. ^ Fitski, Matthijs; van de Ven, Cornelis P.; Hulsker, Caroline C. C.; Bökkerink, Guus M. J.; Terwisscha van Scheltinga, Cecilia E. J.; van den Heuvel-Eibrink, Marry M.; Mavinkurve-Groothuis, Annelies M. C.; van Grotel, Martine; Wijnen, Marc H. W. A.; Klijn, Aart J.; van der Steeg, Alida F. W. (2022-10-01). "Patient-specific hydrogel phantoms for the preoperative simulation of nephron-sparing surgery in Wilms' tumor patients: A feasibility study". Annals of 3D Printed Medicine. 8: 100077. doi:10.1016/j.stlm.2022.100077. ISSN 2666-9641. S2CID 251870073.
  6. ^ van den Heuvel-Eibrink, Marry M.; Hol, Janna A.; Pritchard-Jones, Kathy; van Tinteren, Harm; Furtwängler, Rhoikos; Verschuur, Arnauld C.; Vujanic, Gordan M.; Leuschner, Ivo; Brok, Jesper; Rübe, Christian; Smets, Anne M.; Janssens, Geert O.; Godzinski, Jan; Ramírez-Villar, Gema L.; de Camargo, Beatriz (2017-12-01). "Rationale for the treatment of Wilms tumour in the UMBRELLA SIOP–RTSG 2016 protocol". Nature Reviews Urology. 14 (12): 743–752. doi:10.1038/nrurol.2017.163. ISSN 1759-4820. PMID 29089605. S2CID 9418050.
  7. ^ WhoNamedIt.com: Max Wilms