Wound contracture is a process that may occur during wound healing when an excess of wound contraction, a normal healing process, leads to physical deformity characterized by skin constriction and functional limitations.[1][2][3] Wound contractures may be seen after serious burns and may occur on the palms, the soles, and the anterior thorax.[2] For example, scars that prevent joints from extending or scars that cause an ectropion are considered wound contractures.[1][4]
- ^ a b Sabiston, David C.; Townsend, Courtney M. (2012). Sabiston textbook of surgery : the biological basis of modern surgical practi. Philadelphia, PA: Elsevier Saunders. p. 163. ISBN 978-1-4377-1560-6.
- ^ a b Robbins, Stanley L. (Stanley Leonard); Kumar, Vinay; Cotran, Ramzi S. (2010). Robbins and Cotran pathologic basis of disea. Philadelphia, PA: Saunders/Elsevier. ISBN 978-1-4377-0792-2.
- ^ Shin D1, Minn KW. (2004). "The effect of myofibroblast on contracture of hypertrophic scar". Plast Reconstr Surg. 113 (2): 633–40. doi:10.1097/01.PRS.0000101530.33096.5B. PMID 14758226. S2CID 22189434.
Normally, the myofibroblasts appear in the initial wound healing processes and generate contractile forces to pull both edges of an open wound until it disappears by apoptosis. But as an altered regulation of myofibroblast disappearance, they remain in the dermis and continuously contract the scar, eventually causing scar contracture.
{{cite journal}}: CS1 maint: numeric names: authors list (link) - ^ A. N. Kingsnorth; Aljafri A. Majid (27 April 2006). Fundamentals of Surgical Practice. Cambridge University Press. p. 83. ISBN 978-0-521-67706-6. Retrieved 19 March 2012.