Xanthoma

Xanthoma
A patient's knee showing multiple xanthoma tuberosum[1]
SpecialtyGastroenterology, dermatology Edit this on Wikidata

A xanthoma (pl. xanthomas or xanthomata) (condition: xanthomatosis) is a deposition of yellowish cholesterol-rich material that can appear anywhere in the body in various disease states.[2] They are cutaneous manifestations of lipidosis in which lipids accumulate in large foam cells within the skin.[2] They are associated with hyperlipidemias, both primary and secondary types.[citation needed]

Tendon xanthomas are associated with type II hyperlipidemia, chronic biliary tract obstruction, primary biliary cirrhosis, sitosterolemia and the rare metabolic disease cerebrotendineous xanthomatosis. Palmar xanthomata and tuberoeruptive xanthomata (over knees and elbows) occur in type III hyperlipidemia.[citation needed]

  1. ^ Kumar AA, Shantha GP, Srinivasan Y, Senthil N, Rajkumar K, Paunikar N, Sudhakar M (August 2008). "Acute myocardial infarction in an 18 year old South Indian girl with familial hypercholesterolemia: a case report". Cases Journal. 1 (1): 71. doi:10.1186/1757-1626-1-71. PMC 3301444. PMID 18687118.
  2. ^ a b James WD, Berger TG, Elston DM, Odom RB (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6.