Xipamide

Xipamide

Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy category	contraindication
Routes of administration	By mouth
ATC code	C03BA10 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	95%
Protein binding	98%
Metabolism	glucuronide (30%)
Elimination half-life	5.8 to 8.2 hours
Excretion	kidney (1/3) and bile duct (2/3)
Identifiers
IUPAC name 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
CAS Number	14293-44-8 Y
PubChem CID	26618
IUPHAR/BPS	7900
ChemSpider	24795 N
UNII	4S9EY0NUEC
KEGG	D06341 Y
ChEMBL	ChEMBL517199 N
CompTox Dashboard (EPA)	DTXSID5023744
ECHA InfoCard	100.034.727
Chemical and physical data
Formula	C15H15ClN2O4S
Molar mass	354.81 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=C(C(=CC=C1)C)NC(=O)C2=CC(=C(C=C2O)Cl)S(=O)(=O)N
InChI InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22) N Key:MTZBBNMLMNBNJL-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Xipamide is a sulfonamide diuretic drug marketed by Eli Lilly under the trade names Aquaphor (in Germany) and Aquaphoril (in Austria). It is used for the treatment of oedema and hypertension.