The Youngstown City Series was an OHSAA athletic conference that began play in 1925 and lasted until the end of the 2006–07 school year. Its members were located in the city of Youngstown, Ohio (including all Youngstown City School District high schools), although membership was eventually extended to Timken High School in Canton, Ohio. Some schools closed during the league's tenure, while the rest left before the closings or at the league's demise.