Yunnan Baiyao (or Yunnan Paiyao; simplified Chinese: 云南白药; traditional Chinese: 雲南白藥; pinyin: Yúnnán Báiyào; lit. 'Yunnan White Drug') is a proprietary traditional Chinese medicine marketed and used as a hemostatic product in both human and veterinary alternative medicine.[1] Although Yunnan Baiyao has long been recognized as a pharmaceutical preparation in China, the safety and efficacy of Yunnan Baiyao has not been assessed or established by the FDA, the European Medicines Agency, or the Australian Therapeutic Goods Administration. There is limited evidence regarding its effectiveness in preventing and treating hemorrhagic and pathological conditions in both humans and animals via oral administration.[2] In a limited number of human studies of small sample sizes, administration of Yunnan Baiyao has been shown to correlate with "reduced perioperative bleeding as well as bleeding in various ulcerative–hemorrhagic conditions".[2] It has become popular particularly for animals with hemangiosarcoma.[3] There are multiple routes of drug administration. Yunnan Baiyao is sold in powder, tincture, plaster, paste, aerosol, or tablet form. The medicine, developed by Qu Huangzhang in 1902, is designated as one of two Class-1 protected traditional Chinese medicines, which gives it 20 years of trade protection in China.[4] Yunnan Baiyao products are manufactured and distributed by a state-owned enterprise, Yunnan Baiyao Group (SZSE: 000538) in Yunnan, China.