ZFP36L1

ZFP36L1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1W0V, 1W0W
Identifiers
Aliases	ZFP36L1, BRF1, Berg36, ERF-1, ERF1, RNF162B, TIS11B, cMG1, ZFP36 ring finger protein-like 1, ZFP36 ring finger protein like 1
External IDs	OMIM: 601064; MGI: 107946; HomoloGene: 31276; GeneCards: ZFP36L1; OMA:ZFP36L1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	68,796,253 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	80,159,787 bp
RNA expression pattern
	Top expressed in
	mucosa of paranasal sinus; ; canal of the cervix; ; gastric mucosa; ; right ovary; ; ectocervix; ; nipple; ; left ovary; ; urethra; ; body of uterus; ; right uterine tube;
	Top expressed in
	corneal stroma; ; genital tubercle; ; ventricular zone; ; lactiferous gland; ; lip; ; yolk sac; ; esophagus; ; cardiac muscle tissue of left ventricle; ; superior surface of tongue; ; atrium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; metal ion binding; protein binding; mRNA binding; 14-3-3 protein binding; RNA binding; mRNA 3'-UTR AU-rich region binding; DNA-binding transcription factor activity, RNA polymerase II-specific; mRNA 3'-UTR binding;
Cellular component	cytoplasm; nucleus; cytosol; P-body; ribonucleoprotein complex;
Biological process	spongiotrophoblast layer development; mRNA catabolic process; multicellular organism growth; embryonic organ development; chorio-allantoic fusion; vasculogenesis; proepicardium development; heart development; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; neural tube development; cell population proliferation; regulation of translation; apoptotic process; T cell differentiation in thymus; regulation of gene expression; negative regulation of erythrocyte differentiation; cellular response to insulin stimulus; cellular response to phorbol 13-acetate 12-myristate; ERK1 and ERK2 cascade; positive regulation of intracellular mRNA localization; cellular response to glucocorticoid stimulus; cellular response to transforming growth factor beta stimulus; regulation of keratinocyte differentiation; response to wounding; positive regulation of monocyte differentiation; regulation of transcription, DNA-templated; cellular response to hypoxia; regulation of keratinocyte apoptotic process; regulation of keratinocyte proliferation; phosphatidylinositol 3-kinase signaling; cellular response to tumor necrosis factor; cellular response to epidermal growth factor stimulus; regulation of mRNA 3'-end processing; MAPK cascade; mRNA processing; multicellular organism development; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay; p38MAPK cascade; regulation of mRNA stability; protein kinase B signaling; cellular response to fibroblast growth factor stimulus; regulation of B cell differentiation; positive regulation of fat cell differentiation; regulation of myoblast differentiation; mesendoderm development; mRNA transport; 3'-UTR-mediated mRNA destabilization; cellular response to cAMP; cellular response to peptide hormone stimulus; cellular response to salt stress; regulation of stem cell proliferation; cellular response to raffinose; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; negative regulation of mitotic cell cycle phase transition; transport; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	677
	12192
	ENSG00000185650
	ENSMUSG00000021127
	Q07352
	P23950
	NM_004926; NM_001244698; NM_001244701
	NM_007564
	NP_001231627; NP_001231630; NP_004917
	NP_031590
	Wikidata
View/Edit Human	View/Edit Mouse

Butyrate response factor 1 is a protein that in humans is encoded by the ZFP36L1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185650 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021127 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bustin SA, Nie XF, Barnard RC, Kumar V, Pascall JC, Brown KD, Leigh IM, Williams NS, McKay IA (Aug 1994). "Cloning and characterization of ERF-1, a human member of the Tis11 family of early-response genes". DNA Cell Biol. 13 (5): 449–59. doi:10.1089/dna.1994.13.449. PMID 8024689.
^ "Entrez Gene: ZFP36L1 zinc finger protein 36, C3H type-like 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185650 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021127 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8024689-5] Bustin SA, Nie XF, Barnard RC, Kumar V, Pascall JC, Brown KD, Leigh IM, Williams NS, McKay IA (Aug 1994). "Cloning and characterization of ERF-1, a human member of the Tis11 family of early-response genes". DNA Cell Biol. 13 (5): 449–59. doi:10.1089/dna.1994.13.449. PMID 8024689.

[entrez-6] "Entrez Gene: ZFP36L1 zinc finger protein 36, C3H type-like 1".

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