ZFP91

ZFP91
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2M9A
Identifiers
Aliases	ZFP91, DMS-8, DSM-8, PZF, ZFP-91, ZNF757, FKSG11, ZFP91 zinc finger protein, ZFP91 zinc finger protein, atypical E3 ubiquitin ligase, DSM8
External IDs	MGI: 104854; HomoloGene: 43144; GeneCards: ZFP91; OMA:ZFP91 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	58,621,550 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	12,773,490 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; mucosa of ileum; ; myocardium of left ventricle; ; deltoid muscle; ; cardiac muscle tissue of right atrium; ; cerebellar vermis; ; skin of arm; ; sperm; ; quadriceps femoris muscle; ; cartilage tissue;
	Top expressed in
	ascending aorta; ; aortic valve; ; Rostral migratory stream; ; soleus muscle; ; gastrocnemius muscle; ; tibialis anterior muscle; ; plantaris muscle; ; extensor digitorum longus muscle; ; ankle; ; quadriceps femoris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; nucleic acid binding; ubiquitin-protein transferase activity; transferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleolus;
Biological process	protein K63-linked ubiquitination; activation of NF-kappaB-inducing kinase activity; protein ubiquitination; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	80829
	109910
	ENSG00000186660
	ENSMUSG00000024695
	Q96JP5
	Q62511
	NM_053023; NM_001197051
	NM_053009
	NP_001183980; NP_444251
	NP_443735
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene.^[5]^[6]

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. In addition to the monocistronic transcript originating from this locus, a co-transcribed variant composed of ZFP91 and CNTF sequence has been identified. The monocistronic and co-transcribed variants encode distinct isoforms. The co-transcription of ZFP91 and CNTF has also been observed in mouse.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186660 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024695 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Unoki M, Okutsu J, Nakamura Y (May 2003). "Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia". Int J Oncol. 22 (6): 1217–23. doi:10.3892/ijo.22.6.1217. PMID 12738986.
^ ^a ^b "Entrez Gene: ZFP91 zinc finger protein 91 homolog (mouse)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000186660 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024695 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12738986-5] Unoki M, Okutsu J, Nakamura Y (May 2003). "Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia". Int J Oncol. 22 (6): 1217–23. doi:10.3892/ijo.22.6.1217. PMID 12738986.

[entrez-6] "Entrez Gene: ZFP91 zinc finger protein 91 homolog (mouse)".

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