Zick may refer to:
- Surname
- A family of German artists:
- Bob Zick (1927–2017), American baseball player
- Rolf Zick (1921–2024), German journalist
- Nickname
- Zick, nickname for Isaac
- Zick Rubin (born 1944), American psychologist and lawyer
- Fiction
- Ezekiel Zick, character from the comic book and animated series, Monster Allergy