Zyxin

ZYX
Identifiers
Aliases	ZYX, ESP-2, HED-2, zyxin
External IDs	OMIM: 602002; MGI: 103072; HomoloGene: 31164; GeneCards: ZYX; OMA:ZYX - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	143,391,111 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	42,337,147 bp
RNA expression pattern
	Top expressed in
	body of uterus; ; myometrium; ; left uterine tube; ; granulocyte; ; blood; ; stromal cell of endometrium; ; thoracic aorta; ; right coronary artery; ; ascending aorta; ; smooth muscle tissue;
	Top expressed in
	granulocyte; ; tail of embryo; ; ascending aorta; ; tibiofemoral joint; ; blood; ; aortic valve; ; tunica media of zone of aorta; ; internal carotid artery; ; external carotid artery; ; lip;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; RNA binding;
Cellular component	focal adhesion; plasma membrane; integral component of plasma membrane; stress fiber; cell junction; cytoskeleton; nucleus; cytoplasm; cytosol; phagocytic vesicle;
Biological process	cell-cell signaling; stress fiber assembly; cell adhesion; regulation of inflammatory response; integrin-mediated signaling pathway; cell-matrix adhesion; viral process; transforming growth factor beta receptor signaling pathway; signal transduction; cellular response to interferon-gamma;
	Sources:Amigo / QuickGO
Orthologs
	7791
	22793
	ENSG00000159840; ENSG00000285443
	ENSMUSG00000029860
	Q15942
	Q62523
	NM_001010972; NM_003461; NM_001362783
	NM_001289617; NM_001289618; NM_001289619; NM_011777
	NP_001010972; NP_003452; NP_001349712
	NP_001276546; NP_001276547; NP_001276548; NP_035907
	Wikidata
View/Edit Human	View/Edit Mouse

Zyxin is a protein that in humans is encoded by the ZYX gene.^[5]^[6]^[7]

^ ^a ^b ^c ENSG00000285443 GRCh38: Ensembl release 89: ENSG00000159840, ENSG00000285443 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029860 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zumbrunn J, Trueb B (January 1997). "A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts". Eur J Biochem. 241 (2): 657–63. doi:10.1111/j.1432-1033.1996.00657.x. PMID 8917469.
^ Macalma T, Otte J, Hensler ME, Bockholt SM, Louis HA, Kalff-Suske M, Grzeschik KH, von der Ahe D, Beckerle MC (January 1997). "Molecular characterization of human zyxin". J Biol Chem. 271 (49): 31470–8. doi:10.1074/jbc.271.49.31470. PMID 8940160.
^ "Entrez Gene: ZYX zyxin".

[refGRCh38Ensembl-1] ENSG00000285443 GRCh38: Ensembl release 89: ENSG00000159840, ENSG00000285443 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029860 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8917469-5] Zumbrunn J, Trueb B (January 1997). "A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts". Eur J Biochem. 241 (2): 657–63. doi:10.1111/j.1432-1033.1996.00657.x. PMID 8917469.

[pmid8940160-6] Macalma T, Otte J, Hensler ME, Bockholt SM, Louis HA, Kalff-Suske M, Grzeschik KH, von der Ahe D, Beckerle MC (January 1997). "Molecular characterization of human zyxin". J Biol Chem. 271 (49): 31470–8. doi:10.1074/jbc.271.49.31470. PMID 8940160.

[entrez-7] "Entrez Gene: ZYX zyxin".

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